Do polynucleotides work if you already have wrinkles?

As we age, wrinkles and fine lines become more prominent, leading many to seek effective treatments for skin rejuvenation. Polynucleotides have emerged as a promising option in the realm of aesthetic medicine, known for their regenerative properties. This article explores whether polynucleotides are effective in treating existing wrinkles, with a focus on their application.

Effectiveness on Existing Wrinkles

Immediate Impact

While polynucleotide treatments do not provide instant results, you may notice some immediate effects due to the hydration and plumping of the skin. These immediate changes are often subtle and primarily due to the physical presence of the injected solution rather than the biological activity of the polynucleotides.

Short-term Improvements

In the days following the treatment, you might experience mild redness, swelling, or bruising at the injection sites. These effects are temporary and typically subside within a few hours to a couple of days. During this period, initial improvements in skin texture and hydration may become more noticeable.

Long-term Benefits

Polynucleotide treatments are designed to work gradually by stimulating the skin’s natural regenerative processes. Significant improvements in the appearance of wrinkles and fine lines typically become noticeable within a few weeks. As the polynucleotides promote collagen and elastin production, the skin becomes firmer and more elastic, leading to a reduction in the depth and severity of wrinkles.

Comparing Polynucleotides to Other Treatments

Polynucleotides offer a unique approach to wrinkle treatment compared to other options such as Botox or dermal fillers. While Botox temporarily relaxes facial muscles to smooth out wrinkles, and fillers provide immediate volume to plump the skin, polynucleotides work by enhancing the skin’s natural regenerative capabilities. This means that while the results may take longer to become fully apparent, they are also more natural and sustainable in the long term.

Suitability for Different Skin Types

Polynucleotide treatments are suitable for various skin types and conditions. They are particularly effective for individuals with mature skin showing signs of aging, such as wrinkles, fine lines, and loss of elasticity. The regenerative properties of polynucleotides make them a versatile treatment option for those seeking comprehensive skin rejuvenation.

Choosing the Right Clinic

When considering polynucleotide treatments, it is essential to choose a reputable clinic with experienced practitioners. A thorough consultation should be conducted to assess your skin condition and discuss your aesthetic goals. The practitioner should provide detailed information about the treatment process, potential side effects, and aftercare instructions to ensure a safe and satisfying experience.


Polynucleotides are effective in treating existing wrinkles by promoting collagen and elastin production, improving hydration, and supporting the skin’s natural repair processes. While the results are not instant, the gradual and natural improvements make polynucleotide treatments an excellent choice for long-term skin rejuvenation. If you are based in Clapham or South London and are interested in exploring polynucleotide treatments, our clinic offers expert guidance and personalized care to help you achieve your aesthetic goals safely and effectively.

Contact us today at our BTX London clinic in Balham for a personalised consultation. We’re more than just a Botox clinic—we’re your partners in your aesthetic journey in Clapham.

Feel free to book Botox treatments at our clinic in Balham with Dr. Raman here.

Our clinic has another article about the length of polynucleotides treatments.

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